ea0016p611 | Reproduction | ECE2008
Annunziata Marta
, Trovato Letizia
, Settanni Fabio
, Grande Cristina
, Gallo Davide
, Camanni Marco
, Deltetto Francesco
, Ghigo Ezio
, Granata Riccarda
Somatostatin (SST) and growth hormone-releasing hormone (GHRH) are hypothalamic hormones that, respectively, inhibit and stimulate pituitary GH secretion. In addition, in peripheral tissues somatostatin and its analogues inhibit, whereas GHRH stimulates, both normal and cancer cell growth and survival. Furthermore, both somatostatin receptor 2 (SSTR-2) and GHRH expression have been shown in normal human endometrium. Endometriosis is a common estrogen-dependent disorder defined...